Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps(By similarity).
Categories
Primary Antibodies
Clonality
polyclonal
Description
Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity).
Host
Rabbit
Immunogen
translocase of inner mitochondrial membrane 22 homolog(yeast)
Isotype
IgG
Molecular Weight
20 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
TEX4, TIM22
Antigen
TIMM22
Uniprot
Q9Y584
Gene Id
29928
Research Area
Signal Transduction, Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)