This gene encodes a member of the transglutaminase family. The encoded protein catalyzes formation of protein cross-links between glutamine and lysine residues, often resulting in stabilization of protein assemblies. This reaction is calcium dependent. Mutations in this gene have been associated with acral peeling skin syndrome.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Contributes to the formation of the cornified cell envelope of keratinocytes.
Host
Rabbit
Immunogen
transglutaminase 5
Isotype
IgG
Molecular Weight
80 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
TGMX
Uniprot
O43548
Gene Id
9333
Research Area
Developmental biology, Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)