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Home / Primary Antibodies / Polyclonal Antibodies

TGF-beta 1 antibody

SKU : BHA10808630

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Mfr.No.	FNab08638
Alternative Names	CED ; DPD1 ; LAP ; TGFbeta1 ; TGFB ; TGFB1 ; TGFbeta ; TGF-beta1 ; TGF-β1
Background	TGFB, also named as LAP and TGFB1, is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. TGFB acts synergistically with TGFA in inducing transformation. It also acts as a negative autocrine growth factor. Dysregulation of TGFB activation and signaling may result in apoptosis. Many cells synthesize TGFB and almost all of them have specific receptors for it. TGFB positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. It is highly expressed in bone. Mutation of TGFB are the cause of Camurati-Engelmann disease(CED) which known as progressive diaphyseal dysplasia 1(DPD1).
Categories	Primary Antibodies
Clonality	polyclonal
Description	TGFB, also named as LAP and TGFB1, is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. TGFB acts synergistically with TGFA in inducing transformation. It also acts as a negative autocrine growth factor. Dysregulation of TGFB activation and signaling may result in apoptosis. Many cells synthesize TGFB and almost all of them have specific receptors for it. TGFB positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. It is highly expressed in bone. Mutation of TGFB are the cause of Camurati-Engelmann disease (CED) which known as progressive diaphyseal dysplasia 1 (DPD1).
Host	Rabbit
Immunogen	transforming growth factor, beta 1
Isotype	IgG
Molecular Weight	44 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	CED, DPD1, LAP, TGF beta 1, TGFB, TGFB1, TGFbeta, TGF-beta1, TGF-beta1

Uniprot	P01137
Gene Id	7040
Research Area	Developmental biology, Signal Transduction, Cardiovascular, Immunology, Stem Cells, Neuroscience
Weight	44kDa,observed 25kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, IHC

Description

ELISA ; IHC

Dilution

WB	1:200-1:2000
IHC	1:50-1:500

Tested Application

WB: 1:200-1:2000; IHC: 1:50-1:500

Manual	FNab08638.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808630	FNab08638	100ug	$260		Add to Cart

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