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Home / Primary Antibodies

TERT Polyclonal Antibody

SKU : BHA13715314

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Abbkine Scientific Co., Ltd.

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Mfr.No.	ABP0185
Background	Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by TERT (telomerase reverse transcriptase), and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Alternatively spliced variants encoding different isoforms of telomerase reverse transcriptase have been identified; the full-length sequence of some variants has not been determined. Alternative splicing at this locus is thought to be one mechanism of regulation of telomerase activity
Clonality	Polyclonal
Formulation	The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
Host	Rabbit
Immunogen	Synthetic peptide from human protein at AA range: 1268-1341
Isotype	Rabbit IgG
Reactivity	Human

Gene Id	7015

Concentration	1 mg/ml
Purification	The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
Storage Buffer	PBS, pH 7.4, containing 0.02% Sodium Azide as preservative and 50% Glycerol

Applications	Protein General Reagents

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SKU	Supplier No.	Size	Your price	Quantity
BHA13715314	ABP0185	100ul	$229		Add to Cart

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