Talin is a high-molecular-weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts. Talin serves a function of linking vinculin to the integrins, and, thus, the cytoskeleton to extracellular matrix(ECM) receptors. It has a mass of 270 kD and shares 23% N-terminal identity with ezrin, which has similar functions. TLN gene is mapped to 9p.
Formulation
0.5mg/ml with 1% BSA and 0.01% sodium azide if reconstituted with 0.2ml sterile 1XPBS
Host
Mouse
Immunogen Region
Purified chicken gizzard talin was used as the immunogen for this Talin antibody.
Isotype
IgG1
Predicted Reactivity
Human, bovine
Reactivity
bovine, Human
Recombinant
No
Gene Id
7094
Clone No
8d4
Format
Ascites
Purification
Ascites
Storage
After reconstitution, the Talin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.