T-cell acute lymphocytic leukemia protein 1 (TAL1) also named Stem cell protein,T-cell leukemia/lymphoma protein 5.It is specifically expressed in leukemic stem cell,implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation, serving as a positive regulator of erythroid differentiation. The 38kd, 44kd bands recognized by antibody are the phosphorylated forms of TAL1 and it's isoforms.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of erythroid differentiation (By similarity).
Host
Rabbit
Immunogen
T-cell acute lymphocytic leukemia 1
Isotype
IgG
Molecular Weight
44 kDa
Reactivity
Human, Mouse
Regulatory
RUO
Synonyms
bHLHa17, SCL, Stem cell protein, tal 1, TAL1, TCL5
Uniprot
P17542
Gene Id
6886
Research Area
Epigenetics, Developmental biology, Metabolism, Cardiovascular, Cancer
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)