Adapter linking MAP3K7/TAK1 and TRAF6. Promotes MAP3K7 activation in the IL1 signaling pathway. The binding of 'Lys-63'-linked polyubiquitin chains to TAB2 promotes autophosphorylation of MAP3K7 at 'Thr-187'. Involved in heart development.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Adapter linking MAP3K7/TAK1 and TRAF6. Promotes MAP3K7 activation in the IL1 signaling pathway. The binding of 'Lys-63'- linked polyubiquitin chains to TAB2 promotes autophosphorylation of MAP3K7 at 'Thr-187'. Involved in heart development.
Host
Rabbit
Immunogen
mitogen-activated protein kinase kinase kinase 7 interacting protein 2
Isotype
IgG
Molecular Weight
77 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
KIAA0733, MAP3K7IP2
Uniprot
Q9NYJ8
Gene Id
23118
Research Area
Immunology
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)