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Home / Primary Antibodies / Polyclonal Antibodies

SYTL2 antibody

SKU : BHA10808452

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Mfr.No.	FNab08460
Alternative Names	KIAA1597 ; SGA72M ; SLP2 ; SLP2A
Background	Isoform 1 acts as a RAB27A effector protein and plays a role in cytotoxic granule exocytosis in lymphocytes. It is required for cytotoxic granule docking at the immunologic synapse. Isoform 4 binds phosphatidylserine(PS) and phosphatidylinositol-4,5-bisphosphate(PIP2) and promotes the recruitment of glucagon-containing granules to the cell membrane in pancreatic alpha cells. Binding to PS is inhibited by Ca(2+) while binding to PIP2 is Ca(2+) insensitive.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Isoform 1 acts as a RAB27A effector protein and plays a role in cytotoxic granule exocytosis in lymphocytes. It is required for cytotoxic granule docking at the immunologic synapse. Isoform 4 binds phosphatidylserine (PS) and phosphatidylinositol- 4,5-bisphosphate (PIP2) and promotes the recruitment of glucagon- containing granules to the cell membrane in pancreatic alpha cells. Binding to PS is inhibited by Ca(2+) while binding to PIP2 is Ca(2+) insensitive.
Host	Rabbit
Immunogen	synaptotagmin-like 2
Isotype	IgG
Molecular Weight	100-105 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	KIAA1597, SGA72M, SLP2, SLP2A

Antigen	SYTL2
Uniprot	Q9HCH5
Gene Id	54843
Research Area	Cell Division and Proliferation

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:500-1:2000; IHC: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808452	FNab08460	100ug	$260		Add to Cart

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