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Home / Primary Antibodies / Polyclonal Antibodies

SUZ12 antibody

SKU : BHA10808398

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Mfr.No.	FNab08406
Alternative Names	CHET9 ; JJAZ1 ; KIAA0160
Background	This zinc finger gene has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Polycomb group (PcG) protein. Component of the PRC2/EED- EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.
Host	Rabbit
Immunogen	suppressor of zeste 12 homolog (Drosophila)
Isotype	IgG
Molecular Weight	83 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	CHET9, JJAZ1, KIAA0160

Uniprot	Q15022
Gene Id	23512
Research Area	Epigenetics, Stem Cells, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IP : 1:50 - 1:100

Manual	FNab08406.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808398	FNab08406	100ug	$260		Add to Cart

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