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Home / Primary Antibodies / Polyclonal Antibodies

SURF1 antibody

SKU : BHA10808391

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Mfr.No.	FNab08399
Alternative Names	SURF-1
Background	This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency.
Categories	Primary Antibodies
Clonality	polyclonal
Description	May play a role in mitochondrial respiratory chain complex IV assembly (PubMed:24027061). Probably involved in the biogenesis of the COX complex (PubMed:9843204).
Host	Rabbit
Immunogen	surfeit 1
Isotype	IgG
Molecular Weight	33 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	SURF-1

Uniprot	Q15526
Gene Id	6834
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IF
Description	ELISA ; WB ; IHC ; IF
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab08399.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808391	FNab08399	100ug	$260		Add to Cart

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