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Home / Primary Antibodies / Polyclonal Antibodies

SUPV3L1 antibody

SKU : BHA10808389

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Mfr.No.	FNab08397
Alternative Names	SUV3
Background	Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome(mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded(ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. ATPase and ATP- dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA.
Host	Rabbit
Immunogen	suppressor of var1, 3-like 1
Isotype	IgG
Molecular Weight	70-80 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	SUV3

Uniprot	Q8IYB8
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, IP, WB
Description	ELISA ; IP ; WB
Tested Application	WB: 1:500-1:2000; IP: 1:200-1:1000

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808389	FNab08397	100ug	$260		Add to Cart

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