This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Categories
Primary Antibodies
Clonality
polyclonal
Host
Rabbit
Immunogen
SMT3 suppressor of mif two 3 homolog 2
Isotype
IgG
Molecular Weight
11 kDa
Reactivity
Human, Mouse
Regulatory
RUO
Synonyms
HSMT3, SMT3B, SMT3H2, SUMO3, Smt3A
Uniprot
P61956
Gene Id
6613
Research Area
Epigenetics, Cell Division and Proliferation, Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)