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Home / Primary Antibodies / Polyclonal Antibodies

STXBP2 antibody

SKU : BHA10808352

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Mfr.No.	FNab08360
Alternative Names	UNC18B
Background	This gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Involved in intracellular vesicle trafficking and vesicle fusion with membranes. Contributes to the granule exocytosis machinery through interaction with soluble N- ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Regulates cytotoxic granule exocytosis in natural killer (NK) cells.
Host	Rabbit
Immunogen	syntaxin binding protein 2
Isotype	IgG
Molecular Weight	66 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	UNC18B

Uniprot	Q15833
Gene Id	6813
Research Area	Neuroscience

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, IHC, WB
Description	ELISA ; IHC ; WB
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab08360.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808352	FNab08360	100ug	$280		Add to Cart

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