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Home / Primary Antibodies / Polyclonal Antibodies

STT3A antibody

SKU : BHA10808347

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Mfr.No.	FNab08355
Alternative Names	ITM1 ; TMC
Background	Catalytic subunit of the N-oligosaccharyl transferase(OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum(ER). SST3A seems to be involved in complex substrate specificity. STT3A is present in the majority of OST complexes and mediates cotranslational N-glycosylation of most sites on target proteins, while STT3B-containing complexes are required for efficient cotranslational glycosylation and mediate glycosylation of sites that have been skipped by STT3A.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Catalytic subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). SST3A seems to be involved in complex substrate specificity. STT3A is present in the majority of OST complexes and mediates cotranslational N-glycosylation of most sites on target proteins, while STT3B-containing complexes are required for efficient cotranslational glycosylation and mediate glycosylation of sites that have been skipped by STT3A.
Host	Rabbit
Immunogen	STT3, subunit of the oligosaccharyltransferase complex, homolog A
Isotype	IgG
Molecular Weight	100 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	B5, Integral membrane protein 1, ITM1, STT3 A, STT3A, TMC, Transmembrane protein TMC

Uniprot	P46977
Gene Id	3703
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, IHC, WB
Description	ELISA ; IHC ; WB
Tested Application	WB: 1:1000-1:5000; IHC: 1:20-1:200; IF: 1:20-1:200

Manual	FNab08355.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808347	FNab08355	100ug	$260		Add to Cart

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