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Home / Primary Antibodies / Monoclonal Antibodies

STIM1 antibody

SKU : BHA10808313

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Mfr.No.	FNab08321
Alternative Names	Sim
Background	Plays a role in mediating store-operated Ca(2+) entry(SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores(By similarity). Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+)(CRAC) channel subunit ORAI1(PubMed:16208375). Involved in enamel formation(By similarity). Activated following interaction with TMEM110/STIMATE, leading to promote STIM1 conformational switch(By similarity).
Categories	Primary Antibodies
Clonality	monoclonal
Description	Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores (By similarity). Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit ORAI1 (PubMed:16208375). Involved in enamel formation (By similarity). Activated following interaction with TMEM110/STIMATE, leading to promote STIM1 conformational switch (By similarity).
Host	Mouse
Immunogen	stromal interaction molecule 1
Isotype	IgG2a
Molecular Weight	77kd
Reactivity	Rat, Human, Mouse
Regulatory	RUO
Synonyms	D11S4896E, GOK, STIM1, stromal interaction molecule 1

Uniprot	Q13586
Gene Id	6786
Clone No	4G6
Research Area	Immunology, Neuroscience

Form	liquid
Format	liquid
Purification	Protein A+G purification
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IF
Description	ELISA ; WB ; IF
Tested Application	WB: 1:200-1:2000 IHC: 1:50-1:500

Manual	FNab08321.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808313	FNab08321	100ug	$260		Add to Cart

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