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Home / Primary Antibodies / Polyclonal Antibodies

STAU1 antibody

SKU : BHA10808304

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Mfr.No.	FNab08312
Alternative Names	STAU
Background	Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the same isoform, however, differ in their 5'UTR.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site.
Host	Rabbit
Immunogen	staufen, RNA binding protein, homolog 1 (Drosophila)
Isotype	IgG
Molecular Weight	58 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	STAU

Uniprot	O95793
Gene Id	6780
Research Area	Developmental biology, Metabolism, Neuroscience

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IP
Description	ELISA ; WB ; IP
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

Manual	FNab08312.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808304	FNab08312	100ug	$260		Add to Cart

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