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Home / Primary Antibodies / Polyclonal Antibodies

STAT4 antibody

SKU : BHA10808293

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Mfr.No.	FNab08301
Background	The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Carries out a dual function: signal transduction and activation of transcription. Involved in IL12 signaling.
Host	Rabbit
Immunogen	signal transducer and activator of transcription 4
Isotype	IgG
Molecular Weight	85 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO

Uniprot	Q14765
Gene Id	6775
Research Area	Epigenetics, Signal Transduction, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB
Description	ELISA ; WB
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100

Manual	FNab08301.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808293	FNab08301	100ug	$260		Add to Cart

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