SREBF2, also named as BHLHD2, is a 1141 amino acid protein, which contains 1 bHLH domain and belongs to the SREBP family. SREBF2 localizes in the endoplasmic reticulum membrane and is ubiquitously expressed in adult and fetal tissues. SREBF2 as a transcriptional activator is required for lipid homeostasis. SREBF2 expression is dynamically regulated in response to nutritional and hormonal cues.
Categories
Primary Antibodies
Clonality
polyclonal
Description
SREBF2, also named as BHLHD2, is a 1141 amino acid protein, which contains 1 bHLH domain and belongs to the SREBP family. SREBF2 localizes in the endoplasmic reticulum membrane and is ubiquitously expressed in adult and fetal tissues. SREBF2 as a transcriptional activator is required for lipid homeostasis. SREBF2 expression is dynamically regulated in response to nutritional and hormonal cues.
Host
Rabbit
Immunogen
sterol regulatory element binding transcription factor 2
Isotype
IgG
Molecular Weight
73-75 kDa, 120-130 kDa
Reactivity
Human
Regulatory
RUO
Synonyms
bHLHd2, SREBF2, SREBP 2, SREBP2
Uniprot
Q12772
Gene Id
6721
Research Area
Cardiovascular, Metabolism, Neuroscience
Weight
68 kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)