Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway(By similarity). Binds to the sterol regulatory element 1(SRE-1)(5'-ATCACCCCAC-3'). Has dual sequence specificity binding to both an E-box motif(5'-ATCACGTGA-3') and to SRE-1(5'-ATCACCCCAC-3').
Categories
Primary Antibodies
Clonality
polyclonal
Description
Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway (By similarity). Binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3'). Has dual sequence specificity binding to both an E-box motif (5'-ATCACGTGA-3') and to SRE-1 (5'-ATCACCCCAC-3').
Host
Rabbit
Immunogen
sterol regulatory element binding transcription factor 1
Isotype
IgG
Molecular Weight
125 kDa
Reactivity
Human, Mouse
Regulatory
RUO
Synonyms
BHLHD1, SREBP1
Uniprot
P36956
Gene Id
6720
Research Area
Cardiovascular, Metabolism, Neuroscience
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)