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Home / Primary Antibodies / Polyclonal Antibodies

SOX2 antibody

SKU : BHA10808117

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Mfr.No.	FNab08125
Background	Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206(By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal(By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation(By similarity).
Categories	Primary Antibodies
Clonality	polyclonal
Description	Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).
Host	Rabbit
Immunogen	SRY(sex determining region Y)-box 2
Isotype	IgG
Molecular Weight	34kd
Reactivity	Human, Mouse, Rat, Zebrafish
Regulatory	RUO
Synonyms	ANOP3, MCOPS3, SOX2, Transcription factor SOX 2

Uniprot	P48431
Gene Id	6657
Research Area	Epigenetics, Stem Cells, Metabolism, Neuroscience

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, IF, WB, IHC
Description	ELISA ; IF ; WB ; IHC
Tested Application	WB: 1:2000-1:20000; IHC: 1:50-1:200; IF: 1:50-1:500

Manual	FNab08125.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808117	FNab08125	100ug	$240		Add to Cart

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