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Home / Primary Antibodies / Polyclonal Antibodies

SORBS2 antibody

SKU : BHA10808104

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Mfr.No.	FNab08112
Alternative Names	ARGBP2 ; KIAA0777
Background	Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 or with AKT1 and PAK1, thus mediating AKT1-mediated activation of PAK1. May play a role in the regulation of pancreatic cell adhesion, possibly by acting on WASF1 phosphorylation, enhancing phosphorylation by ABL1, as well as dephosphorylation by PTPN12(PubMed:18559503). Isoform 6 increases water and sodium absorption in the intestine and gall-bladder.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 or with AKT1 and PAK1, thus mediating AKT1-mediated activation of PAK1. May play a role in the regulation of pancreatic cell adhesion, possibly by acting on WASF1 phosphorylation, enhancing phosphorylation by ABL1, as well as dephosphorylation by PTPN12 (PubMed:18559503). Isoform 6 increases water and sodium absorption in the intestine and gall- bladder.
Host	Rabbit
Immunogen	sorbin and SH3 domain containing 2
Isotype	IgG
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	ARGBP2, KIAA0777

Uniprot	O94875
Gene Id	8470
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, IP
Description	ELISA ; IP
Tested Application	IP: 1:200-1:2000

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808104	FNab08112	100ug	$260		Add to Cart

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