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Home / Primary Antibodies / Polyclonal Antibodies

SOCS1 antibody

SKU : BHA10809915

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Mfr.No.	FNab09926
Background	This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.
Clonality	polyclonal
Host	Rabbit
Immunogen	Suppressor of cytokine signaling 1
Immunogen Region	Suppressor of cytokine signaling 1
Isotype	IgG
Molecular Weight	24 kDa
Reactivity	Human, Mouse, Rat
Recommended Dilution	WB: 1:500 - 1:2000; IHC: 1:50-1:200
Synonyms	CIS1, CISH1, JAB, SOCS-1, SSI-1, SSI1, TIP3

Uniprot	O15524
Gene Id	8651
Research Area	Metabolism, Signal Transduction

Form	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Tested Application	WB: 1:500 - 1:2000; IHC: 1:50-1:200

Product Manual	<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab09926.pdf" target="_blank">Data Sheet</ a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809915	FNab09926	100ug	$260		Add to Cart

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