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Home / Primary Antibodies / Polyclonal Antibodies

SNRPA antibody

SKU : BHA10808060

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Mfr.No.	FNab08068
Background	The protein encoded by this gene associates with stem loop II of the U1 small nuclear ribonucleoprotein, which binds the 5' splice site of precursor mRNAs and is required for splicing. The encoded protein autoregulates itself by polyadenylation inhibition of its own pre-mRNA via dimerization and has been implicated in the coupling of splicing and polyadenylation.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1 snRNP is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. SNRPA binds stem loop II of U1 snRNA. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. May bind preferentially to the 5'-UGCAC-3' motif on RNAs.
Host	Rabbit
Immunogen	small nuclear ribonucleoprotein polypeptide A
Isotype	IgG
Molecular Weight	33 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO

Uniprot	P09012
Gene Id	6626
Research Area	Epigenetics, Metabolism, Neuroscience

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Manual	FNab08068.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808060	FNab08068	100ug	$260		Add to Cart

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