Down-regulates NF-kappa-B signaling by competing with RELA for CREBBP/EP300 binding. Involved in the microRNA(miRNA) biogenesis. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Down-regulates NF-kappa-B signaling by competing with RELA for CREBBP/EP300 binding. Involved in the microRNA (miRNA) biogenesis. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA.
Host
Rabbit
Immunogen
Smad nuclear interacting protein 1
Isotype
IgG
Molecular Weight
46-50 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Uniprot
Q8TAD8
Gene Id
79753
Research Area
Epigenetics, Signal Transduction, Metabolism, Neuroscience
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)