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Home / Primary Antibodies / Polyclonal Antibodies

SMURF1 antibody

SKU : BHA10808038

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Mfr.No.	FNab08046
Alternative Names	KIAA1625
Background	E3 ubiquitin-protein ligase that acts as a negative regulator of BMP signaling pathway. Mediates ubiquitination and degradation of SMAD1 and SMAD5, 2 receptor-regulated SMADs specific for the BMP pathway. Promotes ubiquitination and subsequent proteasomal degradation of TRAF family members and RHOA. Plays a role in dendrite formation by melanocytes(PubMed:23999003).
Categories	Primary Antibodies
Clonality	polyclonal
Description	E3 ubiquitin-protein ligase that acts as a negative regulator of BMP signaling pathway. Mediates ubiquitination and degradation of SMAD1 and SMAD5, 2 receptor-regulated SMADs specific for the BMP pathway. Promotes ubiquitination and subsequent proteasomal degradation of TRAF family members and RHOA. Plays a role in dendrite formation by melanocytes (PubMed:23999003).
Host	Rabbit
Immunogen	SMAD specific E3 ubiquitin protein ligase 1
Isotype	IgG
Molecular Weight	83-90 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	KIAA1625

Uniprot	Q9HCE7
Gene Id	57154
Research Area	Epigenetics, Developmental biology, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:500-1:2000; IHC: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808038	FNab08046	100ug	$260		Add to Cart

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