Required for maintenance of X inactivation in females and hypermethylation of CpG islands associated with inactive X. Involved in a pathway that mediates the methylation of a subset of CpG islands slowly and requires the de novo methyltransferase DNMT3B(By similarity). Required for DUX4 silencing in somatic cells.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Required for maintenance of X inactivation in females and hypermethylation of CpG islands associated with inactive X. Involved in a pathway that mediates the methylation of a subset of CpG islands slowly and requires the de novo methyltransferase DNMT3B (By similarity). Required for DUX4 silencing in somatic cells.
Host
Rabbit
Immunogen
structural maintenance of chromosomes flexible hinge domain containing 1
Isotype
IgG
Molecular Weight
220 kDa
Reactivity
Human
Regulatory
RUO
Synonyms
KIAA0650
Uniprot
A6NHR9
Gene Id
23347
Research Area
epigenetics
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)