Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
Host
Rabbit
Immunogen
structural maintenance of chromosomes 4
Isotype
IgG
Molecular Weight
147-150 kDa
Reactivity
Human
Regulatory
RUO
Synonyms
CAPC, SMC4L1
Uniprot
Q9NTJ3
Gene Id
10051
Research Area
Epigenetics, Cell Division and Proliferation, Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)