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Home / Primary Antibodies / Polyclonal Antibodies

SLC25A33 antibody

SKU : BHA10807932

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Mfr.No.	FNab07940
Background	Mitochondrial transporter that imports/exports pyrimidine nucleotides into and from mitochondria(PubMed:25320081). Transports preferentially uracil, thymine, and cytosine(deoxy)nucleoside di-and triphosphates by an antiport mechanism(PubMed:25320081). Also transports guanine but not adenine(deoxy)nucleotides(PubMed:25320081). Is inhibited strongly by pyridoxal 5'-phosphate, 4,7-diphenyl-1,10-phenanthroline, tannic acid, and mercurials(mercury dichloride, mersalyl acid, p-hydroxymercuribenzoate)(PubMed:25320081). Participates in mitochondrial genome maintenance, regulation of mitochondrial membrane potential and mitochondrial respiration(PubMed:20453889). Upon INS or IGF1 stimulation regulates cell growth and proliferation by controlling mitochondrial DNA replication and transcription, the ratio of mitochondria-to nuclear-encoded components of the electron transport chain resulting in control of mitochondrial ROS production(PubMed:20453889, PubMed:17596519). Participates in dendritic cell endocytosis and may associate with mitochondrial oxidative phosphorylation(PubMed:14715278).
Categories	Primary Antibodies
Clonality	polyclonal
Description	Mitochondrial transporter that imports/exports pyrimidine nucleotides into and from mitochondria (PubMed:25320081). Transports preferentially uracil, thymine, and cytosine (deoxy)nucleoside di- and triphosphates by an antiport mechanism (PubMed:25320081). Also transports guanine but not adenine (deoxy)nucleotides (PubMed:25320081). Is inhibited strongly by pyridoxal 5'-phosphate, 4,7-diphenyl-1,10- phenanthroline, tannic acid, and mercurials (mercury dichloride, mersalyl acid, p-hydroxymercuribenzoate) (PubMed:25320081). Participates in mitochondrial genome maintenance, regulation of mitochondrial membrane potential and mitochondrial respiration (PubMed:20453889). Upon INS or IGF1 stimulation regulates cell growth and proliferation by controlling mitochondrial DNA replication and transcription, the ratio of mitochondria-to nuclear-encoded components of the electron transport chain resulting in control of mitochondrial ROS production (PubMed:20453889, PubMed:17596519). Participates in dendritic cell endocytosis and may associate with mitochondrial oxidative phosphorylation (PubMed:14715278).
Host	Rabbit
Immunogen	solute carrier family 25, member 33
Isotype	IgG
Molecular Weight	35-40 kDa
Reactivity	Human
Regulatory	RUO

Antigen	SLC25A33
Uniprot	Q9BSK2
Gene Id	84275
Research Area	Signal Transduction

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB
Description	ELISA ; WB
Tested Application	WB: 1:500-1:2000

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SKU	Supplier No.	Size	Your price	Quantity
BHA10807932	FNab07940	100ug	$280		Add to Cart

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