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Home / Primary Antibodies / Polyclonal Antibodies

SKAP2 antibody

SKU : BHA10807882

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Mfr.No.	FNab07890
Alternative Names	PRAP ; RA70 ; SAPS ; SCAP2 ; SKAP55R
Background	The protein encoded by this gene shares homology with Src kinase-associated phosphoprotein 1, and is a substrate of Src family kinases. It is an adaptor protein that is thought to play an essential role in the Src signaling pathway, and in regulating proper activation of the immune system. This protein contains an amino terminal coiled-coil domain for self-dimerization, a plecskstrin homology (PH) domain required for interactions with lipids at the membrane, and a Src homology (SH3) domain at the carboxy terminus. Some reports indicate that this protein inhibits actin polymerization through interactions with actin assembly factors, and might negatively regulate the invasiveness of tumors by modulating actin assembly. Alternative splicing results in multiple transcript variants encoding different isoforms.
Categories	Primary Antibodies
Clonality	polyclonal
Description	May be involved in B-cell and macrophage adhesion processes. In B-cells, may act by coupling the B-cell receptor (BCR) to integrin activation. May play a role in src signaling pathway.
Host	Rabbit
Immunogen	src kinase associated phosphoprotein 2
Isotype	IgG
Molecular Weight	50 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	PRAP, RA70, SAPS, SCAP2, SKAP55R

Uniprot	O75563
Gene Id	8935
Research Area	Signal Transduction

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IP
Description	ELISA ; WB ; IHC ; IP
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:100

Manual	FNab07890.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10807882	FNab07890	100ug	$260		Add to Cart

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