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Home / Primary Antibodies / Polyclonal Antibodies

SH3PXD2A antibody

SKU : BHA10807828

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Mfr.No.	FNab07836
Alternative Names	FISH ; KIAA0418 ; SH3MD1 ; TKS5
Background	Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases(ADAMs), NADPH oxidases(NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1-or NOX3-dependent reactive oxygen species(ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of beta-amyloid peptide.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of beta-amyloid peptide.
Host	Rabbit
Immunogen	SH3 and PX domains 2A
Isotype	IgG
Molecular Weight	140 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	FISH, KIAA0418, SH3MD1, TKS5

Uniprot	Q5TCZ1
Gene Id	9644
Research Area	Signal Transduction

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IF
Description	ELISA ; WB ; IHC ; IF
Tested Application	WB: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100

Manual	FNab07836.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10807828	FNab07836	100ug	$260		Add to Cart

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