Inhibits the auto-and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death.
Host
Rabbit
Immunogen
SH3-domain binding protein 5(BTK-associated)
Isotype
IgG
Molecular Weight
47 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
SAB
Uniprot
O60239
Gene Id
9467
Research Area
Signal Transduction
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)