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Home / Primary Antibodies / Polyclonal Antibodies

SH3BP4 antibody

SKU : BHA10807822

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Mfr.No.	FNab07830
Alternative Names	BOG25 ; EHB10 ; TTP
Background	May function in transferrin receptor internalization at the plasma membrane through a cargo-specific control of clathrin-mediated endocytosis. Alternatively, may act as a negative regulator of the amino acid-induced TOR signaling by inhibiting the formation of active Rag GTPase complexes. Preferentially binds inactive Rag GTPase complexes and prevents their interaction with the mTORC1 complex inhibiting its relocalization to lysosomes and its activation. Thereby, may indirectly regulate cell growth, proliferation and autophagy.
Categories	Primary Antibodies
Clonality	polyclonal
Description	May function in transferrin receptor internalization at the plasma membrane through a cargo-specific control of clathrin- mediated endocytosis. Alternatively, may act as a negative regulator of the amino acid-induced TOR signaling by inhibiting the formation of active Rag GTPase complexes. Preferentially binds inactive Rag GTPase complexes and prevents their interaction with the mTORC1 complex inhibiting its relocalization to lysosomes and its activation. Thereby, may indirectly regulate cell growth, proliferation and autophagy.
Host	Rabbit
Immunogen	SH3-domain binding protein 4
Isotype	IgG
Molecular Weight	120 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	BOG25, EHB10, TTP

Uniprot	Q9P0V3
Gene Id	23677
Research Area	Developmental biology, Cancer, Signal Transduction, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IF, IP
Description	ELISA ; WB ; IF ; IP
Tested Application	WB: 1:500-1:2000; IP: 1:200-1:1000; IF: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10807822	FNab07830	100ug	$260		Add to Cart

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