This gene encodes one of several enzymes involved in the lysosomal degradation of heparan sulfate. Mutations in this gene are associated with Sanfilippo syndrome A, one type of the lysosomal storage disease mucopolysaccaridosis III, which results from impaired degradation of heparan sulfate. Transcripts of varying sizes have been reported but their biological validity has not been determined.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Catalyzes a step in lysosomal heparan sulfate degradation.
Host
Rabbit
Immunogen
N-sulfoglucosamine sulfohydrolase
Isotype
IgG
Molecular Weight
57 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
HSS
Uniprot
P51688
Gene Id
6448
Research Area
Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)