Involved in transcriptional regulation, through association with histone acetyltransferase(HAT) SAGA-type complexes like the TFTC-HAT, ATAC or STAGA complexes. Specifically recognizes and binds methylated 'Lys-4' of histone H3(H3K4me), with a preference for trimethylated form(H3K4me3). In the SAGA-type complexes, required to recruit complexes to H3K4me. May be involved in MYC-mediated oncogenic transformation.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Involved in transcriptional regulation, through association with histone acetyltransferase (HAT) SAGA-type complexes like the TFTC-HAT, ATAC or STAGA complexes. Specifically recognizes and binds methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3). In the SAGA- type complexes, required to recruit complexes to H3K4me. May be involved in MYC-mediated oncogenic transformation.
Host
Rabbit
Immunogen
coiled-coil domain containing 101
Isotype
IgG
Molecular Weight
33 kDa
Reactivity
Human
Regulatory
RUO
Synonyms
CCDC101
Uniprot
Q96ES7
Gene Id
112869
Research Area
Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)