Protein-lysine N-methyltransferase. Monomethylates 'Lys-310' of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF-kappa-B transcription factor activity(PubMed:21131967). Monomethylates 'Lys-8' of H2AZ(H2AZK8me1)(PubMed:23324626). Required for the maintenance of embryonic stem cell self-renewal(By similarity).
Categories
Primary Antibodies
Clonality
polyclonal
Description
Protein-lysine N-methyltransferase. Monomethylates 'Lys- 310' of the RELA subunit of NF-kappa-B complex, leading to down- regulate NF-kappa-B transcription factor activity (PubMed:21131967). Monomethylates 'Lys-8' of H2AZ (H2AZK8me1) (PubMed:23324626). Required for the maintenance of embryonic stem cell self-renewal (By similarity).
Host
Rabbit
Immunogen
SET domain containing 6
Isotype
IgG
Molecular Weight
53 kDa
Reactivity
Human, Mouse
Regulatory
RUO
Uniprot
Q8TBK2
Gene Id
79918
Research Area
Epigenetics
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)