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Home / Primary Antibodies / Polyclonal Antibodies

SETD1B antibody

SKU : BHA10807758

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Mfr.No.	FNab07766
Alternative Names	KIAA1076 ; KMT2G ; SET1B
Background	Histone methyltransferase that specifically methylates 'Lys-4' of histone H3, when part of the SET1 histone methyltransferase(HMT) complex, but not if the neighboring 'Lys-9' residue is already methylated. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. The non-overalpping localization with SETD1A suggests that SETD1A and SETD1B make non-redundant contributions to the epigenetic control of chromatin structure and gene expression. Specifically tri-methylates 'Lys-4' of histone H3 in vitro.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Histone methyltransferase that specifically methylates 'Lys-4' of histone H3, when part of the SET1 histone methyltransferase (HMT) complex, but not if the neighboring 'Lys- 9' residue is already methylated. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. The non-overalpping localization with SETD1A suggests that SETD1A and SETD1B make non-redundant contributions to the epigenetic control of chromatin structure and gene expression. Specifically tri-methylates 'Lys-4' of histone H3 in vitro.
Host	Rabbit
Immunogen	SET domain containing 1B
Isotype	IgG
Molecular Weight	260 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	KIAA1076, KMT2G, SET1B

Uniprot	Q9UPS6
Gene Id	23067
Research Area	Epigenetics, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IP, IHC
Description	ELISA ; WB ; IP ; IHC
Tested Application	WB: 1:200-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:50-1:500

Manual	FNab07766.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10807758	FNab07766	100ug	$260		Add to Cart

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