The protein encoded by this gene belongs to the serpin family. It is predominantly expressed in the liver and secreted in plasma. It inhibits the activity of coagulation factors Xa and XIa in the presence of protein Z, calcium and phospholipid. Mutations in this gene are associated with venous thrombosis. Alternatively spliced transcript variants have been found for this gene.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Inhibits activity of the coagulation protease factor Xa in the presence of PROZ, calcium and phospholipids. Also inhibits factor XIa in the absence of cofactors.
Host
Rabbit
Immunogen
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
Isotype
IgG
Molecular Weight
51 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
ZPI
Uniprot
Q9UK55
Gene Id
51156
Research Area
Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)