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Home / Primary Antibodies / Polyclonal Antibodies

SEPT7 antibody

SKU : BHA10807718

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Mfr.No.	FNab07726
Alternative Names	CDC10
Background	This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements.
Host	Rabbit
Immunogen	septin 7
Isotype	IgG
Molecular Weight	51 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	CDC10, CDC10 protein homolog, CDC3, Nbla02942, SEPT7, SEPT7A, septin 7

Uniprot	Q16181
Gene Id	989
Research Area	Cell Division and Proliferation

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, IHC, IF, WB
Description	ELISA ; IHC ; IF ; WB
Tested Application	WB: 1:1000 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100

Manual	FNab07726.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10807718	FNab07726	100ug	$260		Add to Cart

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