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Home / Primary Antibodies / Polyclonal Antibodies

SEC14L1 antibody

SKU : BHA10807670

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Mfr.No.	FNab07678
Alternative Names	SEC14L
Background	May play a role in innate immunity by inhibiting the antiviral RIG-I signaling pathway. In this pathway, functions as a negative regulator of DDX58/RIG-I, the cytoplasmic sensor of viral nucleic acids. Prevents the interaction of DDX58 with MAVS/IPS1, an important step in signal propagation(PubMed:23843640). May also regulate the SLC18A3 and SLC5A7 cholinergic transporters(PubMed:17092608).
Categories	Primary Antibodies
Clonality	polyclonal
Description	May play a role in innate immunity by inhibiting the antiviral RIG-I signaling pathway. In this pathway, functions as a negative regulator of DDX58/RIG-I, the cytoplasmic sensor of viral nucleic acids. Prevents the interaction of DDX58 with MAVS/IPS1, an important step in signal propagation (PubMed:23843640). May also regulate the SLC18A3 and SLC5A7 cholinergic transporters (PubMed:17092608).
Host	Rabbit
Immunogen	SEC14-like 1
Isotype	IgG
Molecular Weight	81 kDa, 77 kDa
Reactivity	Human
Regulatory	RUO
Synonyms	SEC14L

Uniprot	Q92503
Gene Id	6397
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB
Description	ELISA ; WB
Tested Application	WB: 1:500-1:2000

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SKU	Supplier No.	Size	Your price	Quantity
BHA10807670	FNab07678	100ug	$280		Add to Cart

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