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Home / Primary Antibodies / Polyclonal Antibodies

SATB2 antibody

SKU : BHA10810585

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Mfr.No.	FNab10798
Background	Binds to DNA, at nuclear matrix-or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcription factor controlling nuclear gene expression, by binding to matrix attachment regions(MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors(HDACs) or coactivators(HATs) directly to promoters and enhancers. Required for the initiation of the upper-layer neurons(UL1) specific genetic program and for the inactivation of deep-layer neurons(DL) and UL2 specific genes, probably by modulating BCL11B expression. Repressor of Ctip2 and regulatory determinant of corticocortical connections in the developing cerebral cortex. May play an important role in palate formation. Acts as a molecular node in a transcriptional network regulating skeletal development and osteoblast differentiation.
Clonality	polyclonal
Host	Rabbit
Immunogen	SATB homeobox 2
Immunogen Region	transducin-like enhancer of split 1
Isotype	IgG
Molecular Weight	69-83 kDa
Reactivity	Human
Recommended Dilution	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Synonyms	DNA binding protein SATB2, KIAA1034, SATB homeobox 2, SATB2

Uniprot	Q9UPW6
Gene Id	23314
Research Area	Developmental biology, Metabolism, Cancer, Neuroscience

Form	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Tested Application	WB: 1?200-1?2000; IHC: 1?20-1?200

Product Manual	<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10855.pdf" target="_blank">Data Sheet</ a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA10810585	FNab10798	100ug	$240		Add to Cart

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