The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.
Categories
Primary Antibodies
Clonality
polyclonal
Description
The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.
Host
Rabbit
Immunogen
SUMO1 activating enzyme subunit 1
Isotype
IgG
Molecular Weight
38 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
AOS1, SUA1, UBLE1A
Uniprot
Q9UBE0
Gene Id
10055
Research Area
Epigenetics, Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)