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Home / Primary Antibodies / Polyclonal Antibodies

S100B antibody

SKU : BHA10807558

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Mfr.No.	FNab07566
Alternative Names	NEF ; ProteinS100B ; S100proteinbetachain ; S100proteinsubunitbeta ; S100 ; S100calciumbindingproteinB ; S100B ; S100beta
Background	Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Weakly binds calcium but binds zinc very tightly- distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.
Host	Rabbit
Immunogen	S100 calcium binding protein B
Isotype	IgG
Molecular Weight	11KD
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	NEF, Protein S100 B, S 100 protein beta chain, S 100 protein subunit beta, S100, S100 calcium binding protein B, S100B, S100beta

Uniprot	P04271
Gene Id	6285
Research Area	Cancer, Immunology, Signal Transduction
Weight	11 kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC, IF

Description

ELISA ; WB ; IHC ; IF

Dilution

WB	1:200-1:1000

Tested Application

WB: 1:200-1:1000; IHC: 1:50-1:500; IF: 1:50-1:500

Manual	FNab07566.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10807558	FNab07566	100ug	$260		Add to Cart

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