The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. Multiple transcript variants encoding different isoforms have been found for this gene.
Clonality
polyclonal
Host
Rabbit
Immunogen
S100 calcium binding protein A8
Immunogen Region
S100 calcium binding protein A8
Isotype
IgG
Molecular Weight
11 kDa, 25 kDa, 40 kDa
Reactivity
Human, Mouse
Recommended Dilution
WB: 1:500-1:2000
Synonyms
CAGA, CFAG, MRP8
Uniprot
P05109
Gene Id
6279
Research Area
Immunology
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Tested Application
WB: 1:500-1:2000
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab09855.pdf" target="_blank">Data Sheet</ a>