The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Facilitates the differentiation and the cornification of keratinocytes.
Host
Rabbit
Immunogen
S100 calcium binding protein A11
Isotype
IgG
Molecular Weight
12 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
MLN70, S100C
Uniprot
P31949
Gene Id
6282
Research Area
Cell Division and Proliferation, Signal Transduction, Metabolism, Immunology, Cancer
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)