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Home / Primary Antibodies / Polyclonal Antibodies

RNF6 antibody

SKU : BHA10807352

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Mfr.No.	FNab07360
Alternative Names	SPG2
Background	E3 ubiquitin-protein ligase mediating 'Lys-48'-linked polyubiquitination of LIMK1 and its subsequent targeting to the proteasome for degradation. Negatively regulates axonal outgrowth through regulation of the LIMK1 turnover. Mediates 'Lys-6' and 'Lys-27'-linked polyubiquitination of AR/androgen receptor thereby modulating its transcriptional activity. May also bind DNA and function as a transcriptional regulator.
Categories	Primary Antibodies
Clonality	polyclonal
Description	E3 ubiquitin-protein ligase mediating 'Lys-48'-linked polyubiquitination of LIMK1 and its subsequent targeting to the proteasome for degradation. Negatively regulates axonal outgrowth through regulation of the LIMK1 turnover. Mediates 'Lys-6' and 'Lys-27'-linked polyubiquitination of AR/androgen receptor thereby modulating its transcriptional activity. May also bind DNA and function as a transcriptional regulator.
Host	Rabbit
Immunogen	ring finger protein(C3H2C3 type) 6
Isotype	IgG
Molecular Weight	78 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	SPG2

Uniprot	Q9Y252
Gene Id	6049
Research Area	Epigenetics, Developmental biology

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IF
Description	ELISA ; WB ; IF
Tested Application	WB: 1:500-1:2000; IF: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10807352	FNab07360	100ug	$280		Add to Cart

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