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Home / Primary Antibodies / Polyclonal Antibodies

RGS5 antibody

SKU : BHA10807264

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Mfr.No.	FNab07272
Background	This gene encodes a member of the regulators of G protein signaling (RGS) family. The RGS proteins are signal transduction molecules which are involved in the regulation of heterotrimeric G proteins by acting as GTPase activators. This gene is a hypoxia-inducible factor-1 dependent, hypoxia-induced gene which is involved in the induction of endothelial apoptosis. This gene is also one of three genes on chromosome 1q contributing to elevated blood pressure. Alternatively spliced transcript variants have been identified.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha (By similarity).
Host	Rabbit
Immunogen	regulator of G-protein signaling 5
Isotype	IgG
Molecular Weight	42 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO

Uniprot	O15539
Gene Id	8490
Research Area	Immunology, Cardiovascular, Signal Transduction

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab07272.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10807264	FNab07272	100ug	$260		Add to Cart

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