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Home / Primary Antibodies / Polyclonal Antibodies

RECQL5 antibody

SKU : BHA10807219

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Mfr.No.	FNab07227
Alternative Names	RECQ5
Background	Isoform beta is a DNA helicase that plays an important role in DNA replication, transcription and repair. Inhibits elongation of stalled transcripts at DNA damage sites by binding to the RNA polymerase II subunit POLR2A and blocking the TCEA1 binding site. Required for mitotic chromosome separation after cross-over events and cell cycle progress. Required for efficient DNA repair, including repair of inter-strand cross-links. Stimulates DNA decatenation mediated by TOP2A. Prevents sister chromatid exchange and homologous recombination.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Isoform beta is a DNA helicase that plays an important role in DNA replication, transcription and repair. Inhibits elongation of stalled transcripts at DNA damage sites by binding to the RNA polymerase II subunit POLR2A and blocking the TCEA1 binding site. Required for mitotic chromosome separation after cross-over events and cell cycle progress. Required for efficient DNA repair, including repair of inter-strand cross-links. Stimulates DNA decatenation mediated by TOP2A. Prevents sister chromatid exchange and homologous recombination.
Host	Rabbit
Immunogen	RecQ protein-like 5
Isotype	IgG
Molecular Weight	50-60 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	RECQL5, DNA helicase, RecQ like type 5, ATP dependent DNA helicase Q5, RecQ protein like 5, RECQ5

Uniprot	O94762
Gene Id	9400
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IF
Description	ELISA ; WB ; IHC ; IF
Tested Application	WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

Manual	FNab07227.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10807219	FNab07227	100ug	$260		Add to Cart

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