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Home / Primary Antibodies / Polyclonal Antibodies

RAD51 antibody

SKU : BHA10807071

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Mfr.No.	FNab07079
Alternative Names	RAD51A ; RECA
Background	Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange(PubMed:26681308). Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange (PubMed:26681308). Part of a PALB2- scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3.
Host	Rabbit
Immunogen	RAD51 homolog
Isotype	IgG
Molecular Weight	37 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	RAD51A, RECA

Uniprot	Q06609
Gene Id	5888
Research Area	Epigenetics, Developmental biology, Cancer, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IP
Description	ELISA ; WB ; IP
Tested Application	WB: 1:500-1:5000; IP: 1:500-1:5000; IHC: 1:50-1:500

Manual	FNab07079.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10807071	FNab07079	100ug	$260		Add to Cart

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