Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species(ROS) by NADPH oxidase.
Categories
Primary Antibodies
Clonality
monoclonal
Description
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase.
Host
Mouse
Immunogen
ras-related C3 botulinum toxin substrate 2(rho family, small GTP binding protein Rac2)
Isotype
IgG1
Molecular Weight
21 kDa
Reactivity
Human, Mouse
Regulatory
RUO
Synonyms
EN 7, Gx, HSPC022, p21 Rac2, RAC2, Small G protein
Uniprot
P15153
Gene Id
5880
Clone No
8F0
Research Area
Signal Transduction
Form
liquid
Format
liquid
Purification
Protein A+G purification
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)