Rab effector protein acting as linker between gamma-adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Involved in KCNH1 channels trafficking to and from the cell membrane(PubMed:22841712). Stimulates RABGEF1 mediated nucleotide exchange on RAB5A.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Rab effector protein acting as linker between gamma- adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Involved in KCNH1 channels trafficking to and from the cell membrane (PubMed:22841712). Stimulates RABGEF1 mediated nucleotide exchange on RAB5A.
Host
Rabbit
Immunogen
rabaptin, RAB GTPase binding effector protein 1
Isotype
IgG
Molecular Weight
100 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
RAB5EP, RABPT5, RABPT5A
Uniprot
Q15276
Gene Id
9135
Research Area
Signal Transduction
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)